This Agreement comprises the entire agreement between you and the Expert Panel for Fragrance Safety (“Expert Panel,” “we,” “our” or “us”) and supersedes any and all prior agreements between you and Expert Panel regarding the subject matter contained therein, including any prior version of this Agreement. *The Expert Panel for Fragrance Safety is an independent body that selects its own members and establishes its own operating procedures. Its conclusions are presented to professional, scientific and medical societies and are published in peer-reviewed scientific journals. RIFM's Expert Panel* concludes that this material is safe under the limits described in this safety assessment. The Weight of Evidence of NESIL is the value determined by the RIFM Expert Panel—an independent group of academic experts with a diversity of scientific specialties and no ties to the fragrance industry, based on a careful analysis of all the available data. Department of Occupational & Environmental Dermatology Prof. dr. Orlando Marques de Paiva, 87, Sao Paulo, CEP 05508-900, Brazil. Universitaet Wuerzburg, Wuerzburg, Germany, Prof. Allison D. Fryer, PhD - Prof. of Pulmonary and Critical Care The booklet also contains answers to some Frequently Asked Questions. Cooperative Institute for Limnology & Ecosystems Research School of Veterinary Medicine and Animal Science The Expert Panel is comprised of renowned independent experts from various scientific fields, including dermatology, toxicology, pathology and environmental science. 2019 Dec ... 2 Member Expert Panel, Columbia University Medical Center, Department of Dermatology, 161 Fort Washington Ave, New York, NY, 10032, USA. Depts. This safety assessment is based on the RIFM Criteria Document (Api et al., 2015) which should be referred to for clarifications. Malmo University Hospital, Malmo, Sweden, Dr. G. Allen Burton, Jr., PhD - Prof. and Director 1Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA. 3 Member RIFM Expert Panel, Malmo University Hospital, Department of Occupational & Environmental Dermatology, Sodra Forstadsgatan … Publications reviewed by the Expert Panel for Fragrance Safety are published on an open-source, publicly available, website sponsored by Elsevier's Food and Chemical Toxicology Journal. The Expert Panel is comprised of internationally known scientists that provide RIFM with guidance relevant to … Prof. dr. Orlando Marques de Paiva, 87, Sao Paulo, CEP 05508-900, Brazil. ; 2 Member Expert Panel, Columbia University Medical Center, Department of Dermatology, 161 Fort Washington Ave., New York, NY 10032, USA. The decisions of the Expert Panel regarding restrictions of use are published as IFRA Standards. The Expert Panel for Fragrance Safety selects its own members, who serve on a rotating basis. 2Member Expert Panel, Columbia University Medical Center, Department of Dermatology, 161 Fort Washington Ave., New York, NY, 10032, USA. The Expert Panel from RIFM hosted the Information Exchange (INFOX) in New Delhi, India in January 2020, in order to share their science to fragrance industry professionals, academics and government oversight officials. Perelman School of Medicine This paper provides details of the approach used by the RIFM Expert Panel (REXPAN), to examine the dermal effects, systemic toxicity and environmental consequences of the use of and exposure to fragrance materials, which allow a reliable determination of safe use under intended conditions. (See below for more about the Expert Panel for Fragrance Safety.) Independent, unbiased scientific support for the safe use of fragrance materials, To provide independent, unbiased, scientific support for the safe use of fragrance materials, To conduct an independent, unbiased assessment of fragrance material safety in accordance with generally accepted scientific criteria, standards, and methodologies, To recommend research on fragrance materials to support safety assessments Most Popular in Company News 1 Ravago Group Acquires Indukern 2 Firmenich, Givaudan, IFF, Symrise Launch Fragrance Council University of Arizona, Tucson, AZ, Prof. Magnus Bruze, MD - Professor University of Pennsylvania, Philadelphia, PA USA, Dr. Terry Schultz - Professor Emeritus Because we focused on the volume of use, RIFM has now assessed and has been granted Expert Panel approval of Safety Assessments for more than 85% of the single component fragrance materials currently in use. The Expert Panel for Fragrance Safety* concludes that this material is safe under the limits described in this safety assessment. The Expert Panel evaluates the safety of fragrance ingredients under conditions of intended use and publishes its results in peer-reviewed scientific journals. 3Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, USA. University of Sao Paulo, Sao Paulo, Brazil, Prof. Dr. Wolfgang Dekant *The Expert Panel for Fragrance Safety is an independent body that selects its own members and establishes its own operating procedures. Additional expertise is provided by adjunct groups with knowledge in genetic toxicity, respiratory science, reproductive effects, environmental fate and epidemiology. ; 2 Member RIFM Expert Panel, Columbia University Medical Center, Department of Dermatology, 161 Fort Washington Ave., New York, NY 10032, USA. The Fragrance Material Safety Resource Center features: Robust Summaries of Fragrance Ingredient Safety Assessments, The 2015 revision of the Criteria for the Research Institute for Fragrance Materials (RIFM) Safety Evaluation Process for Fragrance Ingredients, An archive of earlier publications on the safe use of fragrance materials, Other scientific publications supporting the safe use of fragrance materials globally. Minutes for each meeting are maintained to allow the Panel to track work completed, decisions made, and actions taken. To publish the results of fragrance material safety assessments in peer-reviewed, scientific journals. 5 Member RIFM Expert Panel, Fraunhofer Institute for Toxicology and Experimental Medicine, Nikolai-Fuchs-Strasse 1, 30625, Hannover, Germany. The Panel determines safety of use for fragrance ingredients through consideration of available information and active generation of additional data. ### The Expert Panel for Cosmetic Ingredient Safety (Panel) does not typically review ingredients that function only as fragrance ingredients, because, as fragrances, the evaluation of the safety of these ingredients is the purview of the Research Institute for Fragrance Materials Affiliations 1 Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677 USA. The Research Institute for Fragrance Materials (RIFM) is the global scientific resource on fragrance ingredients for consumers, official agencies and the industry. This safety assessment is based on the RIFM Criteria Document , which should be referred to for clarifications. Step 3: Expert Panel evaluates. The Expert Panel for Fragrance Safety, an independent, international team of researchers and academics with no ties to the fragrance industry, reviews all of RIFM’s work before RIFM submits it for peer-reviewed publication in a reputable scientific journal. The Revised Criteria document for RIFM's Safety Evaluation Process of Fragrance Materials; Robust Summaries of Expert Panel Reviewed Fragrance Material Safety Assessments ; RIFM Scientific Methodology papers; An Archive of RIFM's earlier publications on the safe use of fragrance materials; Other scientific publications supporting RIFM's Mission 5 Member RIFM Expert Panel, Fraunhofer Institute for Toxicology and Experimental Medicine, Nikolai-Fuchs-Strasse 1, 30625, Hannover, Germany. Center in Molecular Toxicology, Department of Biochemistry If the safety assessment does not support current use, the Panel instructs IFRA to issue a Standard. When the original board members of the Research Institute for Fragrance Materials (RIFM) drafted the organization’s Bylaws in 1967, they ensured the objectivity of RIFM’s research, in part, by establishing the Expert Panel for Fragrance Safety, an independent academic panel of dermatologists, toxicologists, chemists, and other scientists with no involvement in the fragrance industry. Dr. Schulz has a long history of serving on advisory/expert panels both on a national and an international level. The Expert Panel for Fragrance Safety . Fraunhofer Inst. The Expert Panel is comprised of internationally known scientists that provide RIFM with guidance relevant to … RIFM safety assessment: additional information provided by the Research Institute for Fragrance Materials, reporting on its studies and findings. When important for consumer and environmental protection, decisions of the Expert Panel regarding restrictions of use are published as IFRA Standards. The Expert Panel respects your privacy and is committed to protecting the privacy of any personally identifiable information that we may collect from you as you use this website. The Expert Panel is an independent group of leading academic scientists from around the world who are recognized in their fields—chemistry, dermatology, and toxicology. Veterinary Pathologist Department of Pathology, University of Tennessee, Knoxville, TN, USA, Prof. Yoshiki Takura, MD, PhD 6 Member RIFM Expert Panel, University of Sao Paulo, School of Veterinary Medicine and Animal Science, Department of Pathology, Av. Oregon Health Science University, Portland, OR, USA, Dr. Daniel C. Liebler, PhD Institut fuer Toxikologie Hamamatsu University School of Medicine, Hamamatsu, Japan, © RESEARCH INSTITUTE FOR FRAGRANCE MATERIALS, RESEARCH INSTITUTE FOR FRAGRANCE MATERIALS. I. Glenn Sipes, PhD (Vice Chair) - Professor & Department Head for Toxicology and Experimental Medicine, Hannover, Germany, Prof. Maria L. Z. Dagli, DVM, PhD - Professor, Department of Pharmacology, College of Medicine Once approved by the Expert Panel, RIFM and the Expert Panel submit their safety assessments for peer-reviewed publication in the journal Food and Chemical Toxicology. It checks whether the data supports current use levels in such a way that there is no risk to consumers. Thank you for visiting the website of the Expert Panel for Fragrance Safety (“Expert Panl,” “we,” “our” or “us”). • Research Institute for Fragrance Materials • Vision: To be the international scientific authority for the safe use of fragrance materials • Non-profit organization funded by Industry (raw material suppliers, fragrance manufacturers, consumer product companies) • Key is the RIFM Expert Panel (REXPAN) In addition, this guide contains a summary of the procedure for setting IFRA Standards, which is based on the RIFM Safety Assessment and the conclusions of the Expert Panel for Fragrance Safety. The Expert Panel is comprised of internationally known scientists that provide RIFM guidance relevant to human health and environmental protection. Highlights of the site include RIFM’s new publication updating the criteria used to process the Fragrance Material Safety Assessments and a selection of Expert Panel and peer reviewed Fragrance Material Safety Assessments that will be added to over time. RIFM fragrance ingredient safety assessment, methyl 2-octynoate, CAS Registry Number 111-12-6 Food Chem Toxicol. EXPERT PANEL FOR FRAGRANCE SAFETY MEMBERS, Prof. Donald V. Belsito, MD (Chair) - Leonard C. Harber Professor of Dermatology *The Expert Panel for Fragrance Safety is an independent body that selects its own members and establishes its own operating procedures. It is comprised of internationally known academic dermatologists, pathologists, toxicologists and environmental scientists. To accomplish this purpose, the Expert Panel is composed of individuals of diverse background and expertise who periodically meet to review data regarding the safe use of fragrance materials referred to it by RIFM, recommend studies when appropriate, and evaluate the safety of fragrance materials under conditions of intended use. Since 2012, he has served on the Expert Panel for Fragrance Safety. 6 Member RIFM Expert Panel, University of Sao Paulo, School of Veterinary Medicine and Animal Science, Department of Pathology, Av. RIFM's activities are reviewed by an independent Expert Panel for Fragrance Safety, which provides strategic guidance, determines scientific study design and interprets test results for relevance to human health and environmental protection. The Expert Panel meets approximately three times per year to review, evaluate, and assess the safety of fragrance materials. 2Member RIFM Expert Panel, Columbia University Medical Center, Department of Dermatology, 161 Fort Washington Ave., New York, NY 10032, USA. The Expert Panel for Fragrance Safety* concludes that this material is safe as described in this safety assessment. The independent Expert Panel for Fragrance Safety oversees the safety assessment process to ensure that it is scientifically sound. Expert Panel for Fragrance Safety Rationale / conclusion: additional explanations by the independent Fragrance Safety Panel. The independent Expert Panel evaluates the data. SC Johnson compliments expert panel for transparency on Fragrance Safety for new public website. Vanderbilt University School of Medicine, Nashville, TN USA, Prof. Trevor M. Penning, PhD For more information about RIFM, visit www.rifm.org. Comparative Medicine and Ecology and Evolutionary Biology The Expert Panel for Fragrance Safety selects its own members, who serve on a rotating basis. It is comprised of internationally known academic dermatologists, pathologists, toxicologists and environmental scientists. The Expert Panel for Fragrance Safety is an independent panel of experts that reviews the activities of the Research Institute for Fragrance Materials (RIFM) for consumers, official agencies, and the industry. All of RIFM's research is guided and reviewed by the independent Expert Panel for Fragrance Safety, made up of an international group of academic dermatologists, pathologists, toxicologists, and environmental and respiratory scientists who have no commercial ties to the fragrance industry. Columbia University Medical Center, New York, NY, Dr. Affiliations 1 Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677 USA. University of Michigan, Ann Arbor, MI, Dr. Jochen Buschmann, Head of Reproductive Toxicology This safety assessment is based on the RIFM Criteria Document (Api et al., 2015; #68218) which should be referred to for clarifications.

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